Obama Promises Faster Transition in Afghanistan













President Obama and Afghan President Hamid Karzai said today that most U.S. combat operations in Afghanistan would end this spring, signaling a quickening troop drawdown that will bring the decade-long war to a close at the end of 2014.


"Our troops will continue to fight alongside Afghans when needed, but let me say it as plainly as I can: Starting this spring, our troops will have a different mission -- training, advising, assisting Afghan forces," Obama announced at an East Room news conference in Washington.


"It will be a historic moment and another step toward full Afghan sovereignty, something I know that President Karzai cares deeply about, as do the Afghan people," he said.


Administration officials said Afghan forces were "exceeding initial expectations" in their capabilities. Afghan security forces are expected to lead 90 percent of security operations across the country in February.


"By the end of next year -- 2014 -- the transition will be complete," Obama said. "Afghans will have full responsibility for their security, and this war will come to a responsible end."


The rosy assessments belied the serious political, economic and security challenges that remain.


Left unanswered by Obama and Karzai: How many U.S. troops might stay after 2014; what their mission would be and whether they could be effective; and whether the forces would have immunity from prosecution in Afghan courts.






Charles Dharapak/AP Photo











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Obama said he was still reviewing recommendations from the Pentagon and will make an announcement in the coming weeks after penning an anticipated bilateral security agreement with Afghanistan. Karzai said the exact number would be up to the United States to decide.


Both leaders confirmed in a statement that the United States "does not seek permanent bases in Afghanistan."


They also agreed today to turn over battlefield combatants held by the U.S. military in Afghanistan to Afghan government control, which has been long-sought by Karzai.


Roughly 66,000 U.S. troops are serving in Afghanistan. The military has proposed keeping several thousand troops in the country after 2014 as advisers, trainers and logistical support for Afghan forces; the White House has said it remains open to pulling out all troops entirely.


Obama's visit with Karzai was the first face-to-face encounter since the November election and since last year's dramatic increase in so-called green-on-blue attacks, when U.S. and NATO soldiers have been killed by the Afghans they are training or working alongside.


There were 45 insider attacks in 2012 that resulted in 62 deaths among coalition forces, including 35 Americans. There has been one attack already in the first 11 days of 2013.


The White House summit included a private Oval Office meeting between Obama, Karzai and Vice President Joe Biden. The trio also attended a private lunch in the Old Family Dining Room.


Karzai Thursday attended meetings with Defense Secretary Leon Panetta and top military brass at the Pentagon, where he was afforded all the pomp and circumstance accorded a head of state: a 21-gun salute, and marching bands and honor guards from the Army, Navy, Air Force, Marines and Coast Guard.


Karzai's relationship with the United States has at times been a rocky one as he has sometimes made critical statements about the allied troop presence in his country. U.S. officials believe he has made those comments out of political expediency to improve his standing with Afghans and show his independence.






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Malian army beats back Islamist rebels with French help


PARIS/BAMAKO (Reuters) - Malian government troops drove back Islamist rebels from a strategic central town after France intervened on Friday with air strikes to halt advances by the militants controlling the country's desert north.


Western governments, particularly former colonial power France, had voiced alarm after the al Qaeda-linked rebel alliance captured the town of Konna on Thursday, a gateway towards the capital Bamako 600 km (375 miles) south.


President Francois Hollande said France would not stand by to watch the rebels push southward. Paris has repeatedly warned that the Islamists' seizure of the country's north in April gave them a base to attack neighboring African countries and Europe.


"We are faced with blatant aggression that is threatening Mali's very existence. France cannot accept this," Hollande, who recently pledged Paris would not to meddle in African affairs, said in a New Year speech to diplomats and journalists.


The president said resolutions by the United Nations Security Council, which in December sanctioned an African-led military intervention in Mali, meant France was acting in accordance with international law.


In Washington, a U.S. official told Reuters the Pentagon was weighing options in Mali, including intelligence-sharing with France and logistics support.


French Foreign Minister Laurent Fabius confirmed France had carried out air strikes against the rebels to prevent them conquering the whole of Mali. He refused to reveal further details, such as whether French troops were on the ground.


France's intervention immediately tipped the military balance of power, with Malian government forces quickly sweeping back into Konna, according to local residents.


"The Malian army has retaken Konna with the help of our military partners. We are there now," Lieutenant Colonel Diaran Kone told Reuters, adding that the army was mopping up Islamist fighters in the surrounding area.


EU SPEEDS UP DEPLOYMENT


A military operation had not been expected until September due to the difficulties of training Malian troops, funding the African force and deploying during the mid-year rainy season. However, Mali's government appealed for urgent military aid from France on Thursday after Islamist fighters took Konna.


EU foreign policy chief Catherine Ashton called on Friday for "accelerated international engagement" and said the bloc would speed up plans to deploy 200 troops to train Malian forces, initially expected in late February.


Blaise Compaore, the president of neighboring Burkina Faso which is acting as a mediator in the Malian crisis, said his country would contribute a contingent of ground troops toward the African Union mission to retake Mali's north.


Burkina Faso had been due to host peace talks between the Malian government and some of the rebel factions on Thursday, but these have been postponed until January 21 due to the outbreak of hostilities.


The capture of Konna by the rebels - who have imposed strict Sharia Islamic law in northern Mali - had caused panic among residents in the towns of Mopti and Sevare, 60 km (40 miles) to the south. Calm returned, however, after residents reported Western soldiers and foreign military aircraft arriving late on Thursday at Sevare's airport - the main one in the region.


Military analysts said the Western soldiers may have been the first deployment of French special forces.


They voiced doubt, however, whether Friday's action heralded the start of the final operation to retake northern Mali - a harsh, sparsely populated terrain the size of France - as neither the equipment nor ground troops were ready.


"We're not yet at the big intervention," said Mark Schroeder, director for Sub-Saharan Africa analysis for the global risk and security consultancy Stratfor. He said France had been forced to act when the Islamists bore down on Sevare, a vital launching point for future military operations.


"The French realized this was a red line that they could not permit to be crossed," he said.


STATE OF EMERGENCY


More than two decades of peaceful elections had earned Mali a reputation as a bulwark of democracy in a part of Africa better known for turmoil - an image that unraveled in a matter of weeks after a military coup last March that paved the way for the Islamist rebellion.


Mali is Africa's third largest gold producer and a major cotton grower, and home to the fabled northern desert city of Timbuktu - an ancient trading hub and UNESCO World Heritage site that hosted annual music festivals before the rebellion.


Interim President Dioncounda Traore, under pressure for bolder action from Mali's military, declared a state of emergency on Friday. Traore will fly to Paris for talks with Hollande on Wednesday.


"Every Malian must henceforth consider themselves a soldier," Traore said on state TV, calling on mining and telecoms companies to contribute to the war effort. He said he requested French air support with the blessing of West African allies.


The chief of operations for Mali's Defence Ministry said Nigeria and Senegal were among the other countries providing military support on the ground. Fabius said these countries had not taken part in the French operation.


A spokesman for the Nigerian air force said planes had been deployed to Mali for a reconnaissance mission, not for combat.


The French foreign ministry stepped up its security alert on Mali and parts of neighboring Mauritania and Niger on Friday, extending its red alert - the highest level - to include Bamako. France has eight nationals in Islamist hands in the Sahara after a string of kidnappings.


A spokesman for al Qaeda's north African arm AQIM urged France, in a video posted on the Internet, to reconsider its intervention. "Stop your assault against us or you are digging your own sons' graves," said Abdallah Al-Chinguetti.


(Additional reporting by Richard Valdmanis in Dakar, Pascal Fletcher in Johannesburg, Phil Stewart in Washington, Alexandria Sage, John Irish and Elizabeth Pineau in Paris; writing by Daniel Flynn; editing by Giles Elgood)



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Captain blames faulty brakes, motor for NY ferry accident






NEW YORK: The captain of a packed ferry that crashed into a New York City pier injuring 74 people blamed malfunctioning brakes and a faulty motor for the accident, US investigators said Thursday.

"As the boat was coming in, the captain found that the reverse thrust was not operating as anticipated," said Robert Sumwalt of the National Transportation Safety Board, which is investigating the accident.

The captain said there was also a problem with the motor on the vessel, telling investigators that at some point "both diesel engines shut off," while he steered it toward the pier, Sumwalt told reporters.

There were 326 passengers and five crew on board the ferry at the time of Wednesday's mishap.

The accident took place during the morning rush hour at Pier 11 in lower Manhattan's East River, not far from Wall Street. The ferry was arriving from New Jersey.

Sumwalt said the captain, who is 36 years old, has 12 years of experience as a ferryboat captain and tested negative for alchohol use, as did the entire crew. Results of drug testing have yet to be completed, he said.

Some witnesses reported that the ferry, the Seastreak Wall Street, was going too quickly as it approached the pier.

Weather conditions were good at the time of the accident, with hardly any wind and good visibility.

Dozens of ferries bring thousands of commuters from New Jersey or Brooklyn to Manhattan every day, but accidents are rare.

The most serious mishap, in October 2003, killed 11 people and injured 70 others when a Staten Island ferry slammed into a pier at full speed.

- AFP/ck



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Will send more men to border: Martyr's village

SHER NAGAR (MATHURA): Sher Nagar, the village of deceased Lance Naik Hemraj Singh, is unfazed by the events of Tuesday. For the past three decades, it has sent its young men to fight for the country. Currently, there are eight men from the village on duty at the Pakistan and China borders. Hemraj's death has only strengthened their resolve.

"The men are calling us since they heard about Hemraj. They are telling us when we are sending more men to the borders," said Tejinder Singh Jadaon, who himself believes he has a good chance in the armed forces. There are several others who are trying to get into the paramilitary forces.

The villagers though have a tough stand on India's meek response every time such an incident gets reported. This incident, they say, only shows the futility of bilateral talks and cricket series. Rather, they want more people-to-people contact to ease tension. "The politicians are of no use. The people of Pakistan who lead the government have repeatedly back stabbed us whether it was Kargil or the 26/11 massacre. Why we do not just let the people of two countries sort out the problems through non-diplomatic channels?" said Bhagwan Singh, a teacher in the village.

Most youngsters in the village know who all are in the village. More importantly, they know each one's regiment and even the present posting. "Two of the brothers — Shyam Sunder and Ranveer — are at Jammu and Kashmir and Congo respectively. Deen Narayan Singh, a veteran, is in China. We have been sending the men regularly but since 1996 there has been a rush," said Dharamveer Singh, the village sarpanch but does not recall why that year was important. "I guess there were more vacancies," he said.

Tejinder though explains the love for the uniform. "It is the best government job that provides a good and honourable life along with a steady income. The only other government job here is that of a teacher. But then, one of our lads have made it to Delhi police and others might follow," he reasoned.

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Flu season strikes early and, in some places, hard


NEW YORK (AP) — From the Rocky Mountains to New England, hospitals are swamped with people with flu symptoms. Some medical centers are turning away visitors or making them wear face masks, and one Pennsylvania hospital set up a tent outside its ER to deal with the feverish patients.


Flu season in the U.S. has struck early and, in many places, hard.


While flu normally doesn't blanket the country until late January or February, it is already widespread in more than 40 states, with about 30 of them reporting some major hot spots. On Thursday, health officials blamed the flu for the deaths of 20 children so far.


Whether this will be considered a bad season by the time it has run its course in the spring remains to be seen.


"Those of us with gray hair have seen worse," said Dr. William Schaffner, a flu expert at Vanderbilt University in Nashville.


The evidence so far points to a moderate season, Schaffner and others say. It looks bad in part because last year was unusually mild and because the main strain of influenza circulating this year tends to make people sicker and really lay them low.


David Smythe of New York City saw it happen to his 50-year-old girlfriend, who has been knocked out for about two weeks. "She's been in bed. She can't even get up," he said.


Also, the flu's early arrival coincided with spikes in a variety of other viruses, including a childhood malady that mimics flu and a new norovirus that causes vomiting and diarrhea, or what is commonly known as "stomach flu." So what people are calling the flu may, in fact, be something else.


"There may be more of an overlap than we normally see," said Dr. Joseph Bresee, who tracks the flu for the Centers for Disease Control and Prevention.


Most people don't undergo lab tests to confirm flu, and the symptoms are so similar that it can be hard to distinguish flu from other viruses, or even a cold. Over the holidays, 250 people were sickened at a Mormon missionary training center in Utah, but the culprit turned out to be a norovirus, not the flu.


Flu is a major contributor, though, to what's going on.


"I'd say 75 percent," said Dr. Dan Surdam, head of the emergency department at Cheyenne Regional Medical Center, Wyoming's largest hospital. The 17-bed emergency room saw its busiest day ever last week, with 166 visitors.


The early onslaught has resulted in a spike in hospitalizations. To deal with the influx and protect other patients from getting sick, hospitals are restricting visits from children, requiring family members to wear masks and banning anyone with flu symptoms from maternity wards.


One hospital in Allentown, Pa., set up a tent this week for a steady stream of patients with flu symptoms. But so far "what we're seeing is a typical flu season," said Terry Burger, director of infection control and prevention for the hospital, Lehigh Valley Hospital-Cedar Crest.


On Wednesday, Boston declared a public health emergency, with the city's hospitals counting about 1,500 emergency room visits since December by people with flu-like symptoms.


All the flu activity has led some to question whether this year's flu shot is working. While health officials are still analyzing the vaccine, early indications are that it's about 60 percent effective, which is in line with what's been seen in other years.


The vaccine is reformulated each year, based on experts' best guess of which strains of the virus will predominate. This year's vaccine is well-matched to what's going around. The government estimates that between a third and half of Americans have gotten the vaccine.


In New York City, 57-year-old Judith Quinones skipped getting a flu shot this season and suffered her worst case of flu-like illness in years. She was laid up for nearly a month with fever and body aches. "I just couldn't function," she said.


But her daughter got the vaccine. "And she got sick twice," Quinones said.


Europe is also suffering an early flu season, though a milder strain predominates there. Flu reports are up, too, in China, Japan, the West Bank, the Gaza Strip, Algeria and the Republic of Congo. Britain has seen a surge in cases of norovirus.


On average, about 24,000 Americans die each flu season, according to the CDC. That's an estimate — the agency does not keep a running tally of adult flu deaths each year, only for children. Some state health departments do keep count, and they've reported dozens of flu deaths so far.


Flu usually peaks in midwinter. Symptoms can include fever, cough, runny nose, head and body aches and fatigue. Some people also suffer vomiting and diarrhea, and some develop pneumonia or other severe complications.


Most people with flu have a mild illness and can help themselves and protect others by staying home and resting. But people with severe symptoms should see a doctor. They may be given antiviral drugs or other medications to ease symptoms.


Flu vaccinations are recommended for everyone 6 months or older. Of the 20 children killed by the flu this season, only two were fully vaccinated.


___


AP Medical Writer Maria Cheng in London contributed to this report.


___


Online:


CDC flu: http://www.cdc.gov/flu/index.htm


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Hero Teacher Talks Shooter into Dropping Gun













A California high school teacher is being hailed a hero for talking a 16-year-old shooter into putting down his gun and turning himself in after opening fire on a classroom and wounding another student, police said.


The student victim was taken to a nearby hospital and remains in critical but stable condition, Kern County Sheriff Donny Youngblood told reporters on Thursday.


The teacher, whose name has not yet been officially released by authorities, helped evacuate nearly two dozen students out a door at Taft Union High School in Taft, Calif., while calmly engaging the young gunman, who is a student at Taft Union, in conversation.






Chris McCullah/The Californian/ZUMA













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The teacher and a campus supervisor, who responded to the gunfire and arrived at the classroom, helped convince the teenager to stop shooting.


"They talked him into putting the shotgun down," Youngblood said.


The shooting began around 9 a.m. in the school's science building and sheriff's deputies were on the scene within one minute of the call. An armed security guard who is typically at the school was not on campus because he had been snowed in, the sheriff said.


Two other students received minor injuries: One reported hearing loss and the other fell over a table. The teacher was shot with a pellet, but refused medical treatment, according to police.


The school's 900 students were evacuated from the building and many of them were met by parents within minutes of the first 911 calls.


Today's shooting comes less than month after 20-year-old Adam Lanza opened fire on an elementary school in Newtown, Conn. killing 20 children and six adults.



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String of bombings kill 101, injure 200 in Pakistan


QUETTA, Pakistan (Reuters) - At least 101 people were killed in bombings in two Pakistani cities on Thursday in one of the country's bloodiest days in recent years, officials said, with most casualties caused by sectarian attacks in Quetta.


The bombings underscored the myriad threats Pakistani security forces face from homegrown Sunni extremist groups, the Taliban insurgency in the northwest and the less well-known Baloch insurgency in the southwest.


On Thursday evening, two coordinated explosions killed at least 69 people and injured more than 100 in Quetta, the provincial capital of Balochistan, said Deputy Inspector of Police Hamid Shakil.


The first attack, in a crowded snooker hall, was a suicide bombing, local residents said. About ten minutes later, a car bomb exploded, they said. Five policemen and a cameraman were among the dead from that blast.


The attacks happened in a predominately Shia neighborhood and banned sectarian group Lashkar-e-Jhangvi claimed responsibility. The extremist Sunni group targets Shias, who make up about 20 percent of Pakistani's population.


Targeted killings and bombings of Shia communities are common in Pakistan, and rights groups say hundreds of Shia were killed last year. Militant groups in Balochistan frequently bomb or shoot Shia passengers on buses travelling to neighboring Iran.


The killers are rarely caught and some Shia activists say militants work alongside elements of Pakistan's security forces, who see them as a potential bulwark against neighboring India.


Many Pakistanis fear their nation could become the site of a regional power struggle between Saudi Arabia, source of funding for Sunni extremist groups, and Iran, which is largely Shia.


But sectarian tensions are not the only source of violence.


The United Baloch Army claimed responsibility for a blast in Quetta's market earlier in the day. It killed 11 people and injured more than 40, mostly vegetable sellers and secondhand clothes dealers, police officer Zubair Mehmood said. A child was also killed.


The group is one of several fighting for independence for Balochistan, an arid, impoverished region with substantial gas, copper and gold reserves, which constitutes just under half of Pakistan's territory and is home to about 8 million of the country's population of 180 million.


SWAT BOMBING


In another incident Thursday, 21 were killed and more than 60 injured in a bombing when people gathered to hear a religious leader speak in Mingora, the largest city in the northwestern province of Swat, police and officials at the Saidu Sharif hospital said.


"The death toll may rise as some of the injured are in critical condition and we are receiving more and more injured people," said Dr. Niaz Mohammad.


It has been more than two years since a militant attack has claimed that many lives in Swat.


The mountainous region, formerly a tourist destination, has been administered by the Pakistani army since their 2009 offensive drove out Taliban militants who had taken control.


But Talibans retain the ability to attack in Swat and shot schoolgirl campaigner Malala Yousufzai in Mingora last October.


A Taliban spokesman said they were not responsible for Thursday's bombing.


(Additional reporting by Jibran Ahmad in Peshawar, Pakistan; Writing by Katharine Houreld; Editing by Mark Heinrich and Jason Webb)



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EU leaders want UK in union, but not treaty change






LONDON: European leaders on Wednesday stressed the importance of keeping Britain in the EU, but said they opposed treaty changes demanded by Prime Minister David Cameron.

"Britain is an essential part of the EU," Irish Prime Minister Enda Kenny said during a conference in Dublin marking the beginning of his country's six-month presidency of the bloc.

"Great Britain has great value and is a very important member of the EU," added EU President Herman Van Rompuy.

The two leaders highlighted the importance of the union for British businesses, saying that it was essential for them that Britain remained a full and active member.

A majority of Britons favour severing all ties with the union, according to polls, and Cameron is expected to deliver a speech within the next few days spelling out his views on the country's relationship with Brussels.

He insisted last year that he supported Britain's membership, but that he wanted to negotiate a "new agreement" which would allow it to opt out of certain directives.

Kenny and Van Rompuy both repeated their opposition to any treaty changes.

"I don't see a reopening of the treaties, I don't see an issue in treaty change for any individual countries," said the Irish prime minister.

Irish Deputy Prime Minister Eamon Gilmore stressed that the top concern of European citizens, "whether from Liverpool or Limerick", was unemployment.

Van Rompuy reiterated that it would be possible to change the treaties after the 2014 European elections, but added that he strongly supported deeper EU integration as opposed to an "a la carte" union.

He pointed out that there was already scope for increasing EU partnership.

"We don't need, at this stage, a treaty change," he said. "We can deliver for a deeper EU within the treaties."

- AFP/jc



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Born of rape, left alone and bereft

BHUBANESWAR/AHMEDABAD: He's just four and is lost and bewildered. Not only is Raghav in a new school in a strange place, he's away from the fond gaze of his doting grandparents. For no fault of his.

In 2007, his mother Meera was raped in Khaprakhol area of Balangir in Orissa. Distraught and depressed, she approached local NGO Kalyan when she was two-months pregnant. "We counselled her and convinced her not to go for an abortion," says Meenakshi Purohit of Kalyan.

But life has been a constant struggle since. Her son was refused admission in school when the teachers discovered that he was born of rape. Later, Meera got him admitted to a school unfamiliar with her status. But for that, she had to leave the security of her parents' home and shift to another place. She's now finding it difficult to earn a living. What's worse, the accused is still absconding.

Meera's story is the story of countless rape victims left to fend for themselves and their children in a cruel and uncaring world. In Orissa alone, there are at least a dozen children in recent times born out of rapes who lead a hand-to-mouth existence in the absence of family or government support.

In Deogarh district, a 14-year-old disabled girl raped by a 70-year-old is jeered by everyone. After she gave birth in July, she's been living with her parents. But her father, a daily wage labourer, can't support her. "She has visited several government offices for help but no one cares," says a local.

There are also cases of parents deserting their raped daughters. A minor who was raped in Balangir is now working in a beauty parlour and fends for her three-year-old daughter after her parents wanted nothing to do with her. Besides the cold indifference of families, there is the insensitivity of authorities.

A Class IV dropout in Kuchinda who conceived after being raped by a neighbour has got little help despite the then state commission for women chairperson Jyoti Panigrahi discussing her rehabilitation with district authorities.

"A rape victim, even if she is not pregnant, is entitled to be rehabilitated under the Criminal Injuries Relief and Rehabilitation Boards scheme. Each victim gets Rs 2 lakh compensation. Collectors should ensure its implementation," says Panigrahi.

But there has been hope and rehabilitation for some. In contrast to these bleak cases, the Patan gang-rape victim in Gujarat has got her life back on the rails. The victim, 23, teaches in a school in rural Gujarat. After a tiring day at work, she heads home to a loving husband who runs a mobile repair shop and a baby boy who makes her run around in circles.

Her amazing comeback story is an example of how rape victims should be treated. After being sexually assaulted by six teachers at Patan Primary Teacher's Training College (PTC) in 2008, she used to hallucinate about monster gurus despite being ensconced in the safety of a home run by an NGO. She would be held, comforted and told that it was all over.

She was lucky. The boy in love with her also proposed marriage. "His proposal in 2010 was something I felt would never happen to me. Even my in-laws treat me like a daughter," she says. Despite post-traumatic stress for months, she passed her studies with distinction and got a government job. She's now at peace. "I wish the outrage over rape allows people to open their hearts and accept rape victims as wives and daughter-in-laws," she says plaintively.

(Some names changed to protect identity)

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Retooling Pap test to spot more kinds of cancer


WASHINGTON (AP) — For years, doctors have lamented that there's no Pap test for deadly ovarian cancer. Wednesday, scientists reported encouraging signs that one day, there might be.


Researchers are trying to retool the Pap, a test for cervical cancer that millions of women get, so that it could spot early signs of other gynecologic cancers, too.


How? It turns out that cells can flake off of tumors in the ovaries or the lining of the uterus, and float down to rest in the cervix, where Pap tests are performed. These cells are too rare to recognize under the microscope. But researchers from Johns Hopkins University used some sophisticated DNA testing on the Pap samples to uncover the evidence — gene mutations that show cancer is present.


In a pilot study, they analyzed Pap smears from 46 women who already were diagnosed with either ovarian or endometrial cancer. The new technique found all the endometrial cancers and 41 percent of the ovarian tumors, the team reported Wednesday in the journal Science Translational Medicine.


This is very early-stage research, and women shouldn't expect any change in their routine Paps. It will take years of additional testing to prove if the so-called PapGene technique really could work as a screening tool, used to spot cancer in women who thought they were healthy.


"Now the hard work begins," said Hopkins oncologist Dr. Luis Diaz, whose team is collecting hundreds of additional Pap samples for more study and is exploring ways to enhance the detection of ovarian cancer.


But if it ultimately pans out, "the neat part about this is, the patient won't feel anything different," and the Pap wouldn't be performed differently, Diaz added. The extra work would come in a lab.


The gene-based technique marks a new approach toward cancer screening, and specialists are watching closely.


"This is very encouraging, and it shows great potential," said American Cancer Society genetics expert Michael Melner.


"We are a long way from being able to see any impact on our patients," cautioned Dr. Shannon Westin of the University of Texas MD Anderson Cancer Center. She reviewed the research in an accompanying editorial, and said the ovarian cancer detection would need improvement if the test is to work.


But she noted that ovarian cancer has poor survival rates because it's rarely caught early. "If this screening test could identify ovarian cancer at an early stage, there would be a profound impact on patient outcomes and mortality," Westin said.


More than 22,000 U.S. women are diagnosed with ovarian cancer each year, and more than 15,000 die. Symptoms such as pain and bloating seldom are obvious until the cancer is more advanced, and numerous attempts at screening tests have failed.


Endometrial cancer affects about 47,000 women a year, and kills about 8,000. There is no screening test for it either, but most women are diagnosed early because of postmenopausal bleeding.


The Hopkins research piggybacks on one of the most successful cancer screening tools, the Pap, and a newer technology used along with it. With a standard Pap, a little brush scrapes off cells from the cervix, which are stored in a vial to examine for signs of cervical cancer. Today, many women's Paps undergo an additional DNA-based test to see if they harbor the HPV virus, which can spur cervical cancer.


So the Hopkins team, funded largely by cancer advocacy groups, decided to look for DNA evidence of other gynecologic tumors. It developed a method to rapidly screen the Pap samples for those mutations using standard genetics equipment that Diaz said wouldn't add much to the cost of a Pap-plus-HPV test. He said the technique could detect both early-stage and more advanced tumors. Importantly, tests of Paps from 14 healthy women turned up no false alarms.


The endometrial cancers may have been easier to find because cells from those tumors don't have as far to travel as ovarian cancer cells, Diaz said. Researchers will study whether inserting the Pap brush deeper, testing during different times of the menstrual cycle, or other factors might improve detection of ovarian cancer.


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